The paper deals with the analysis of the role of mobile business in small, medium and large enterprises. M-Business uses mobile technologies to improve efficiency in conducting business processes. It covers all areas as well as e-business, but also provides a number of additional opportunities. The biggest disadvantage of m-business is the need to have an Internet connection at any time of m-business. A review of the literature found that the role of m-business depends on the size of the entity, as well as activities and the nature of business. Such findings were confirmed by a practical survey conducted on 50 respondents who are employed in businesses of different sizes. Certain answers point to the still underdeveloped awareness and skepticism towards m-business. From the answers of the respondents, it can be concluded that the biggest advantage of m-business is saving time, and the biggest disadvantage is the necessity of having an Internet connection at all times. It can also be concluded that one of the disadvantages is the cost of implementation because most respondents use free m-business applications. Regardless of any negative or indifferent attitudes, the vast majority of employees believe that m-business is the future of business. Such a setting is acceptable because m-business has been developing progressively in recent years and is gaining in popularity.