Music plays an important role in the life of every man, and especially children. Research shows that music and musical activities are especially important for the development of children with disabilities. Music improves coordination, speech and memory of students on the autistic spectrum but also develops other skills. It encourages positive emotions, fellowship with others, improves socio-emotional and physical development. The goal of this research was to qualitatively show how students with autistic disorder react to certain teaching methods in Music classes, how teachers of students with autistic disorder prepare and adapt the teaching content, methods, outcomes from the subject curriculum, and what they pay attention to when planning and preparing for class, which were also research questions. The paper first describes the importance and influence of music on humans, and especially describes the influence of music on children. Then the types of difficulties are described, especially those groups of difficulties that are associated with the autistic spectrum. The autistic spectrum and the way of teaching students from the autistic spectrum are described in detail, with an emphasis on Music. Data for the purposes of this research was collected by video recording Music lessons, written interviewing of teachers, implementation of evaluation sheets with students of the autism spectrum, and insight into teachers' preparations and individualized student curricula. All collected data are described in the paper, and after each type of lesson (lesson with an emphasis on learning a new song, lesson with an emphasis on active listening to music and lesson with an emphasis on creativity) a discussion is written. A concluding discussion is written at the very end. This paper presents concrete examples of work in the classroom with students from the autistic spectrum. The paper can serve as an example of situations and ways of working with students on the autism spectrum. It can be used by all primary school teachers as examples of working with students of the autistic spectrum, as well as by all parents, teaching assistants and teaching students.